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Image Question-34

What is the Diagnosis of Image? Nephron, CC BY-SA 3.0 https://creativecommons.org/licenses/by-sa/3.0, via Wikimedia Commons What...

Primary brain tumors

Tumor-like malformations of Brain include all except A. Epidermoid tumorsB. Colloid cystC. Pineal tumorsD. Craniopharyngioma...

Papez circuit 

Papez circuit is involved in function of A. memory B. sensory processing C. motor function...

Memory

Haptic memory is a type of sensory memory that represents A. visual stimuli B. auditory stimuli...

Pott Puffy Tumor

Pott puffy tumor results from A. Osteomyelitis B. Hyperplasia C. Neoplasia D. Osteoma Pott Puffy...


Edema – MCQs

Which of the following is characteristic finding in severe renal disease?A. Pedal edemaB. Sacral edemaC….

Babesia

Maltese-cross form is a characteristic feature of which of the following parasite?A. Schistosoma mansoniB. Brugia malayiC….

CRAB criteria

CRAB criteria is used for – A. Chronic Myeloid Leukemia B. Multiple Myeloma C.Renal Cell…

Medicine MCQs – 23

Under normal circumstances, free hemoglobin released by hemolysis is removed by -

Correct! Wrong!

Clinical settings - Haptoglobin assay is used to screen for and monitor intravascular hemolytic anemia.
In intravascular hemolysis, free hemoglobin will be released into circulation and hence haptoglobin will bind the hemoglobin. This causes a decline in haptoglobin levels.

Which is the most common site for thrombosis in PNH patients?

Correct! Wrong!

Hepatic vein thrombosis (Budd-Chiari syndrome) is recognized as one of the most common sites of thrombosis
Hepatic failure is a common cause of mortality in PNH

All of the following are CORRECT about thrombosis in PNH patients EXCEPT -

Correct! Wrong!

Cerebral venous thrombosis is common
Cerebral venous system is the second most frequent location of thrombosis after hepatic veins. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602837/

All of the following are useful in treatment of Paroxysmal nocturnal hemoglobinuria as required EXCEPT:

Correct! Wrong!

Long-term glucocorticoids not useful and contraindicated

Eculizumab is a recombinant humanized monoclonal antibody against the complement protein -

Correct! Wrong!

Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5

Which of the following support a diagnosis of hemolysis?

Correct! Wrong!

Decrease in haptoglobin and Low Hb and Hematocrit support a diagnosis of hemolysis

All of the following are correct about Eculizumab EXCEPT -

Correct! Wrong!

Meningococcal vaccination is recommended at least 2 weeks before receiving eculizumab

All of the following are correct for Paroxysmal nocturnal hemoglobinuria EXCEPT:

Correct! Wrong!

In PNH - Mutation of the X-linked gene phosphatidylinositol glycan class A (PIGA), produces a deficiency in the glycosylphosphatidylinositol (GPI) protein, which is responsible for anchoring other protein moieties to the surface of erythrocytes.

Which medicine dramatically alters the natural course of PNH, reducing symptoms and disease complications as well as improve survival?

Correct! Wrong!

Eculizumab- is a medication used to treat
- paroxysmal nocturnal hemoglobinuria (PNH)
- atypical hemolytic uremic syndrome (aHUS)
- generalized myasthenia gravis
- neuromyelitis optica

Most common finding in Paroxysmal nocturnal hemoglobinuria is -

Correct! Wrong!

Paroxysmal nocturnal hemoglobinuria (PNH) - most common- hemolytic anemia, hemoglobinuria, and shortness of breath.
Other findings - thrombosis, renal insufficiency, and bone marrow failure.

Gait disturbances

Gait disturbancesGaitCause Of GaitCause 1Antalgic Gaitpain2Vaulting gaitcommon in children with limb length discrepancypelvic droop, decreased…

Medicine MCQs-22

What is the primary defect of type 2 renal tubular acidosis?

Correct! Wrong!

type 2 RTA - Proximal HCO3 - reabsorption
type 1 RTA - Diminished distal H+ secretion

Which is the most common cause of metabolic acidosis in hospitalized patients?

Correct! Wrong!

Lactic acidosis is the most common cause of metabolic acidosis in hospitalized patients.

What is the primary defect of type 1 renal tubular acidosis?

Correct! Wrong!

Primary defect of type 1 renal tubular acidosis -impairment in hydrogen ion secretion in the distal tubule

Which of the following is the major cause of Hyperchloremic metabolic acidosis?

Correct! Wrong!

Hyperchloremic metabolic acidosis is a pathological state that results from bicarbonate loss, rather than acid production or retention.

All of the following are the exogenous causes of hyperchloremic acidosis EXCEPT -

Correct! Wrong!

Exogenous causes of hyperchloremic acidosis -
Ammonium chloride supplement
Hydrochloric acid supplement
Large volume resuscitation with normal saline

It is called as elevated anion gap when anion gap is -

Correct! Wrong!

elevated anion gap - when anion gap is >12 mEq/L

Metabolic acidosis is defined as a reduced serum pH, and an abnormal serum bicarbonate concentration of -

Correct! Wrong!

Metabolic acidosis is defined as a reduced serum pH, and an abnormal serum bicarbonate concentration of <22 mEq/L

Salicylate poisoning causes typically -

Correct! Wrong!

Two of the most common and notable causes of increased anion gap metabolic acidosis -
High anion gap metabolic acidosis conditions include -
diabetic ketoacidosis (DKA)
salicylate poisoning

Delta ratio is a formula that can be used to assess -

Correct! Wrong!

Delta ratio, or "delta-delta", is a formula that can be used to assess elevated anion gap metabolic acidosis

Most common cause of a low anion gap is -

Correct! Wrong!

Low anion gap is often due to hypoalbuminemia.
Albumin is an anionic protein and its loss results in the retention of other negatively charged ions such as chloride and bicarbonate.
As bicarbonate and chloride anions are used to calculate the anion gap, there is a subsequent decrease.

Auer rods

Which conditions are associated with Auer rods ? Also called – Auer bodies These are…

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