Immunology MCQs
Which is the most common Immunoglobulin?
IgG
In the process of binding of IgE to human mast cells and basophils which of the following is mainly responsible?
The α chain is responsible for IgE binding, and the β and γ chains provide for signal transduction
Which is the primary mediator of vasodilation in "niacin flush"?
Primary mediator of vasodilation in "niacin flush" - Prostaglandin D2
Which is the largest immunoglobulin?
IgM is the largest antibody and the first one to be synthesized in response to an antigen or microbe, accounting for 5% of all immunoglobulins present in the blood. IgM typically exists as polymers of identical subunits, with a pentameric form as the prevalent one.
Binding of IgE to human Mast cells and Basophils is called as -
Binding of IgE to human mast cells and basophils - Called sensitization
Sensitization - Prepares these cells for subsequent antigen specific activation.
Which is the major prostaglandin produced by mast cells?
Prostaglandin D2
Which is the least common Immunoglobulin?
IgE:
IgE is the least prevalent one, with a serum concentration 10,000 times lower than IgG.
Which is the smallest immunoglobulin?
IgG
Prostanoids includes Prostaglandins and ---------
Prostaglandins and thromboxane A2 (TXA2), collectively termed prostanoids
Which immunoglobulin is an important part of the immune response against infection by certain parasitic worms?
IgE