Carvallo sign is a clinical sign found in patients with
A. Mitral stenosis
B. Mitral regurgitation
C. Tricuspid regurgitation
D. Tricuspid stenosis
ANSWER
C. Tricuspid regurgitation
Following is TRUE about Carvallo sign
A. Murmur of Tricuspid regurgitation becomes softer during expiration
B. Murmur of Tricuspid regurgitation becomes louder during expiration
C. Murmur of Tricuspid regurgitation becomes louder during inspiration
D. Murmur of Tricuspid regurgitation becomes softer during inspiration
ANSWER
C. Murmur of Tricuspid regurgitation becomes louder during inspiration
Carvallo sign – What is the mechanism?
During inspiration in Tricuspid regurgitation
-venous blood flow into the right atrium and ventricle are increases
– stroke volume of the right ventricle during systole increases.
– blood flow from the right ventricle into the right atrium is larger during inspiration,
– cause the murmur to become louder during Inspiration
Carvallo’s sign
1. What is Carvallo’s sign most commonly associated with?
A. Aortic stenosis
B. Mitral valve prolapse
C. Tricuspid regurgitation
D. Pulmonary stenosis
💬 Explanation: Carvallo’s sign is an auscultatory finding in tricuspid regurgitation, where the murmur becomes louder during inspiration due to increased venous return to the right heart.
2. Which of the following best describes Carvallo’s sign?
A. Decreased murmur intensity with inspiration
B. Murmur that radiates to the neck
C. Increased intensity of systolic murmur during inspiration
D. Diastolic murmur intensified during expiration
💬 Explanation: Carvallo’s sign refers to the increase in intensity of a right-sided systolic murmur (typically tricuspid regurgitation) with inspiration.
3. Why does Carvallo’s sign occur?
A. Decreased intrathoracic pressure increases left heart filling
B. Increased venous return to right heart during inspiration
C. Pulmonary vasoconstriction during inspiration
D. Valve calcification
💬 Explanation: Inspiration increases venous return to the right heart, making right-sided murmurs louder, as seen in Carvallo’s sign.
4. In which cardiac condition is Carvallo’s sign a key distinguishing feature?
A. Tricuspid regurgitation
B. Mitral stenosis
C. Aortic regurgitation
D. Hypertrophic cardiomyopathy
💬 Explanation: Carvallo’s sign helps differentiate tricuspid regurgitation from left-sided murmurs, as it becomes louder with inspiration.
5. Carvallo’s sign helps to differentiate which of the following?
A. Mitral from aortic murmurs
B. Tricuspid from mitral regurgitation
C. Aortic stenosis from pulmonic stenosis
D. Innocent murmur from pathologic murmur
💬 Explanation: Carvallo’s sign differentiates tricuspid regurgitation (right-sided) from mitral regurgitation (left-sided), as the former increases with inspiration.
6. Carvallo’s sign is typically used to differentiate which of the following?
A. Right and left atrial enlargement
B. Pericardial effusion vs tamponade
C. Right vs left-sided heart murmurs
D. Systolic vs diastolic murmurs
💬 Carvallo’s sign helps differentiate right-sided murmurs (which increase with inspiration) from left-sided murmurs.
7. Which maneuver enhances Carvallo’s sign?
A. Deep inspiration
B. Valsalva maneuver
C. Standing up quickly
D. Handgrip exercise
💬 Deep inspiration increases venous return to the right heart, accentuating right-sided murmurs and making Carvallo’s sign evident.
8. In which valvular lesion is Carvallo’s sign most prominently seen?
A. Aortic stenosis
B. Tricuspid regurgitation
C. Mitral regurgitation
D. Pulmonary stenosis
💬 Carvallo’s sign is classically associated with tricuspid regurgitation, where the murmur increases with inspiration.
9. What is the primary physiological mechanism behind Carvallo’s sign?
A. Increased venous return during inspiration
B. Decreased systemic resistance
C. Reduced intrathoracic pressure during expiration
D. Reduced preload
💬 Deep inspiration increases venous return to the right side of the heart, which can intensify right-sided murmurs—this is the basis of Carvallo’s sign.
10. Carvallo’s sign is negative in which of the following conditions?
A. Mitral regurgitation
B. Tricuspid stenosis
C. Tricuspid regurgitation
D. Pulmonary hypertension
💬 Mitral regurgitation is a left-sided murmur and does not show Carvallo’s sign since it does not increase with inspiration.
11. Carvallo’s sign can be best appreciated using which of the following tools?
A. ECG
B. Stethoscope
C. Chest X-ray
D. Echocardiogram
💬 Carvallo’s sign is a clinical auscultatory finding best appreciated with a stethoscope during physical examination.
12. Which of the following clinical findings would most likely accompany a positive Carvallo’s sign?
A. Holosystolic murmur that increases with inspiration
B. Opening snap followed by diastolic rumble
C. Ejection click and systolic crescendo-decrescendo murmur
D. Mid-diastolic murmur at apex
💬 A holosystolic murmur that increases during inspiration is characteristic of tricuspid regurgitation and positive Carvallo’s sign.
13. Which statement is true regarding Carvallo’s sign?
A. It indicates a right-sided murmur that increases with inspiration
B. It confirms left ventricular outflow obstruction
C. It disappears on deep inspiration
D. It is specific for pulmonary embolism
💬 Carvallo’s sign is characterized by the intensification of right-sided heart murmurs (especially tricuspid regurgitation) during inspiration.
14. Which murmur will typically increase in intensity with inspiration?
A. Aortic stenosis
B. Tricuspid regurgitation
C. Mitral stenosis
D. Aortic regurgitation
💬 Among the listed options, **tricuspid regurgitation** is the right-sided murmur that **increases with inspiration**, a hallmark of Carvallo’s sign.
15. Carvallo’s sign is most useful in differentiating:
16. Which of the following mechanisms best explains the Carvallo sign?
A. Decreased venous return during inspiration
B. Increased right-sided heart filling during inspiration
C. Atrial contraction against closed AV valve
D. Pulmonary hypertension causing regurgitation
💬 The Carvallo sign reflects increased right-sided heart filling during inspiration, enhancing the murmur of tricuspid regurgitation.
17. The Carvallo sign is most useful in distinguishing between which two murmurs?
A. Aortic vs. Pulmonary stenosis
B. Mitral regurgitation vs. Tricuspid regurgitation
C. VSD vs. ASD
D. Hypertrophic cardiomyopathy vs. AS
💬 Carvallo sign helps distinguish tricuspid regurgitation (intensifies with inspiration) from mitral regurgitation (not affected by respiration).
18. Which condition is most likely to demonstrate a positive Carvallo sign?
A. Mitral stenosis
B. Aortic regurgitation
C. Tricuspid regurgitation
D. Pulmonary embolism
💬 Tricuspid regurgitation classically exhibits a murmur that becomes louder during inspiration—a hallmark of the Carvallo sign.
19. Carvallo sign relies on which respiratory phase to enhance murmur intensity?
A. Expiration
B. Inspiration
C. Both phases equally
D. Valsalva maneuver
💬 Inspiration increases venous return to the right heart, intensifying right-sided murmurs like tricuspid regurgitation.
20. In a patient with suspected infective endocarditis and a murmur increasing with inspiration, what does Carvallo sign suggest?
A. Mitral valve vegetation
B. Tricuspid valve involvement
C. Pulmonary stenosis
D. Aortic root abscess
💬 A murmur that intensifies during inspiration in infective endocarditis suggests right-sided valve involvement—most commonly the tricuspid valve.
Carvallo sign
Point
Detail
1️⃣
Carvallo Sign is a clinical auscultatory sign.
2️⃣
It helps differentiate right-sided from left-sided heart murmurs.
3️⃣
Carvallo Sign is positive when a murmur increases during inspiration.
4️⃣
It indicates a right-sided murmur, usually tricuspid regurgitation.
5️⃣
Inspiration increases venous return to the right heart, enhancing right-sided murmurs.
6️⃣
Left-sided murmurs (e.g., mitral regurgitation) typically do not increase with inspiration.
7️⃣
Named after Dr. José Manuel Rivero Carvallo, a Mexican cardiologist.
8️⃣
Best appreciated at the lower left sternal border with the patient supine.
9️⃣
Particularly valuable in diagnosing tricuspid valve disorders.
🔟
Helps avoid misdiagnosis of mitral regurgitation in the presence of tricuspid regurgitation.
1️⃣1️⃣
A positive Carvallo sign also suggests elevated right atrial pressures.
1️⃣2️⃣
Can be accentuated by deep inspiration or sitting forward.
1️⃣3️⃣
Not useful in severe right heart failure with poor venous return.
1️⃣4️⃣
Useful during bedside clinical examination in resource-limited settings.
1️⃣5️⃣
Carvallo sign is most specific when systolic murmur intensity increases with inspiration.
1️⃣6️⃣
It may help differentiate tricuspid stenosis from mitral stenosis.
1️⃣7️⃣
Has diagnostic relevance in endocarditis affecting the tricuspid valve.
1️⃣8️⃣
Should be assessed along with jugular venous pressure and other right-heart signs.
1️⃣9️⃣
In patients with pacemakers or prosthetic valves, interpretation can be complex.
2️⃣0️⃣
Still holds value in the era of echocardiography for bedside assessments.
Cardiology MCQs-8
Most sensitive and specific test for myocardial damage A. Troponin I B. CK-MB C. Lactate dehydrogenase D. Ischemia-modified albumin Which is most specific for myocardial injury? A. Troponin T B. CK-MB C. Troponin I D. Troponin C Which is earliest to peak in myocardial injury? A. Troponin I B. Myoglobin C. Lactate dehydrogenase D. Ischemia-modified albumin Glycogen phosphorylase isoenzyme BB isoform of the enzyme exists in A. Heart and Kidney B. Heart and Brain C. Heart and Liver D. Heart and Pancreas Homocysteine is a cardiac biomarker classified as Biomarkers of A. Myocardial injury B. Myocardial Necrosis C. Hemodynamic stress...
Carvallo’s sign
BySteven Lome, MD
Rivero-Carvallo sign
Accentuation of the murmur of tricuspid stenosis with inspiration. Mexican cardiologist José Manuel Rivero Carvallo (1905–1993) in 1946